Physiology of stress and its integration into the nervous and endocrine system.

Main Article Content

Emilio Eduardo Romero Romero
José Young
Rigoberto Salado-Castillo

Abstract

Currently stress can be defined as the linking mechanism between a stressor and its target organ, resulting in a psychophysiological response, characterized by glucocorticoids release.


The stress response is mediated by two interrelated systems, these are: The sympathetic-adrenomedular system (SAM) and the hypothalamic-pituitary-adrenocortical system (HPA). The SAM system is a region of the sympathetic division of the autonomic nervous system, which releases adrenaline from the adrenal medulla; on the other hand, the HPA axis is responsible for the production of glucocorticoids.


The primary objective of this review is to define and classify stress and to indicate the stress most affected system as a secondary objective. Finally, we will indicate the effect of stress on memory and the relationship between stress and weight gain.


The stress response can occur with the activation of different physiological pathways, one with immediate effects, the second with intermediate effects and the last one called chronic stress.


After being stimulated by stressful events, HPA causes the elevation of glucocorticoids that stimulate food intake, particularly high-calorie foods, this intake can be used by individuals as a method of coping with stress and leading to obesity finally.

Article Details

How to Cite
1.
Romero Romero EE, Young J, Salado-Castillo R. Physiology of stress and its integration into the nervous and endocrine system. Rev Méd Cient [Internet]. 2021May24 [cited 2025Oct.6];32(1):61-70. Available from: https://www.revistamedicocientifica.org/index.php/rmc/article/view/535
Section
Review Articles
Author Biographies

Emilio Eduardo Romero Romero, Universidad de Panamá. Departamento de Fisiología y Comportamiento Animal.

Licenciado en Biología.
Profesor en el Departamento de Fisiología y Comportamiento Animal. Universidad de Panamá.

José Young, Universidad de Panamá. Departamento de Fisiología y Comportamiento Animal.

Licenciado en Biología. Universidad de Panamá. 

Doctor en Fisiología y Biofísica. Georgetown University, School of Medicine.

Profesor en el Departamento de Fisiología y Comportamiento Animal. Universidad de Panamá.

Profesor de Biofísica. Facultad de Medicina. Universidad de Panamá.  

Rigoberto Salado-Castillo, Universidad de Panamá. Facultad de Psicología.

Licienciado en Psicología. Universidad de Panamá.

Doctor en Ciencias Biomédicas, con especialidad en Fisiología y Fisiopatología Humana. Universidad Nacional Autónoma de México.